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Enyel De Los Santos
P
HOU
2026 season
- GP
- 66
- W-L
- 3-3
- ERA
- 4.80
- WHIP
- 1.25
- K
- 67
- IP
- 71.1
Game log
| Date | Opp | Result | Dec | IP | H | ER | BB | K |
|---|---|---|---|---|---|---|---|---|
| Sep 18 | vs ATL | L 2-6 | - | 2.0 | 2 | 2 | 0 | 3 |
| Sep 16 | vs KC | L 2-5 | - | 1.1 | 2 | 2 | 2 | 2 |
| Sep 13 | @TB | L 4-14 | - | 0.2 | 4 | 2 | 0 | 0 |
| Sep 9 | @PHI | L 7-11 | - | 0.2 | 0 | 0 | 0 | 1 |
| Sep 5 | vs AZ | L 3-4 | - | 1.2 | 0 | 0 | 0 | 2 |
| Sep 4 | vs AZ | W 3-1 | - | 0.1 | 1 | 0 | 1 | 0 |
| Aug 31 | vs CWS | W 6-3 | W | 1.0 | 0 | 0 | 3 | 0 |
| Aug 29 | @NYM | L 2-6 | - | 2.0 | 1 | 0 | 0 | 2 |
| Aug 26 | @NYY | L 3-9 | - | 1.2 | 1 | 2 | 1 | 3 |
| Aug 23 | vs ATH | L 6-7 | - | 0.1 | 3 | 3 | 0 | 1 |
| Aug 21 | vs ATH | W 4-0 | - | 1.0 | 0 | 0 | 0 | 0 |
| Aug 18 | vs LAA | L 1-3 | - | 1.1 | 1 | 0 | 0 | 0 |
| Aug 14 | vs SEA | W 10-7 | W | 1.0 | 1 | 1 | 0 | 0 |
| Aug 12 | @SF | W 2-1 | - | 0.1 | 1 | 0 | 1 | 0 |
| Aug 11 | @SF | L 1-4 | - | 0.2 | 2 | 1 | 0 | 0 |
| Aug 8 | @SD | L 2-3 | - | 2.0 | 0 | 0 | 0 | 2 |
| Aug 4 | vs TOR | W 7-2 | - | 2.0 | 1 | 0 | 0 | 1 |
| Aug 1 | vs TEX | W 5-4 | - | 0.2 | 1 | 1 | 0 | 1 |
| Jul 31 | vs TEX | W 11-2 | - | 0.2 | 1 | 0 | 0 | 0 |
| Jul 28 | @LAA | W 3-2 | - | 1.0 | 0 | 0 | 0 | 2 |
| Jul 26 | @CWS | L 3-12 | - | 1.0 | 3 | 2 | 0 | 1 |
| Jul 22 | vs MIA | W 5-2 | - | 1.0 | 1 | 0 | 0 | 2 |
| Jul 20 | vs MIA | W 8-5 | W | 1.1 | 1 | 0 | 0 | 2 |
| Jul 18 | vs BAL | L 2-4 | L | 1.0 | 2 | 1 | 1 | 2 |
| Jul 17 | vs BAL | L 2-3 | - | 1.0 | 0 | 0 | 1 | 0 |
| Jul 12 | @TEX | L 5-6 | - | 1.0 | 0 | 0 | 0 | 0 |
| Jul 11 | @TEX | W 9-3 | - | 1.0 | 1 | 0 | 0 | 1 |
| Jul 7 | @WSH | W 6-3 | - | 1.0 | 1 | 0 | 0 | 0 |
| Jul 6 | @WSH | L 11-12 | - | 1.0 | 0 | 0 | 1 | 2 |
| Jul 3 | vs TB | L 1-3 | - | 2.0 | 2 | 1 | 0 | 2 |
| Jun 30 | vs MIN | W 6-4 | - | 1.0 | 0 | 0 | 0 | 1 |
| Jun 28 | @DET | W 7-5 | - | 1.0 | 2 | 1 | 1 | 1 |
| Jun 25 | @DET | W 2-1 | S | 1.0 | 2 | 1 | 0 | 0 |
| Jun 23 | @TOR | W 9-7 | - | 1.1 | 3 | 2 | 0 | 0 |
| Jun 22 | @TOR | L 2-4 | L | 1.1 | 2 | 1 | 0 | 2 |
| Jun 17 | vs DET | W 4-2 | - | 1.0 | 0 | 0 | 0 | 1 |
| Jun 16 | vs DET | W 4-2 | - | 1.0 | 0 | 0 | 0 | 1 |
| Jun 13 | @KC | W 8-7 | - | 0.1 | 2 | 2 | 1 | 0 |
| Jun 12 | @KC | W 10-8 | - | 0.1 | 3 | 3 | 0 | 1 |
| Jun 10 | @LAA | L 2-3 | - | 1.1 | 0 | 0 | 2 | 0 |
| Jun 8 | @LAA | W 5-4 | - | 1.0 | 2 | 1 | 0 | 1 |
| Jun 5 | vs ATH | W 5-1 | - | 1.2 | 0 | 0 | 0 | 2 |
| Jun 4 | vs PIT | L 1-5 | - | 1.0 | 1 | 0 | 0 | 1 |
| Jun 2 | vs PIT | L 6-10 | - | 1.0 | 0 | 0 | 0 | 2 |
| May 28 | @TEX | W 5-1 | - | 0.2 | 0 | 0 | 1 | 1 |
| May 27 | @TEX | W 4-3 | S | 1.2 | 0 | 0 | 0 | 3 |
| May 23 | @CHC | W 3-0 | - | 1.0 | 0 | 0 | 0 | 1 |
| May 22 | @CHC | W 4-2 | - | 1.2 | 0 | 0 | 0 | 1 |
| May 19 | @MIN | W 2-1 | - | 0.2 | 1 | 0 | 0 | 0 |
| May 16 | vs TEX | W 4-1 | - | 0.1 | 3 | 1 | 0 | 0 |
| May 13 | vs SEA | W 4-3 | - | 1.1 | 0 | 0 | 0 | 2 |
| May 9 | @CIN | L 1-3 | - | 1.0 | 0 | 0 | 0 | 2 |
| May 6 | vs LAD | L 2-12 | - | 1.0 | 0 | 0 | 0 | 0 |
| May 3 | @BOS | W 3-1 | - | 1.0 | 1 | 0 | 0 | 1 |
| May 2 | @BOS | W 6-3 | - | 1.2 | 1 | 1 | 0 | 1 |
| Apr 30 | @BAL | W 11-5 | - | 1.0 | 1 | 0 | 1 | 2 |
| Apr 26 | vs NYY | W 7-4 | - | 1.0 | 4 | 3 | 0 | 0 |
| Apr 22 | @CLE | W 2-0 | S | 1.1 | 1 | 0 | 1 | 1 |
| Apr 21 | @CLE | L 5-8 | L | 0.1 | 2 | 3 | 1 | 0 |
| Apr 19 | vs STL | L 5-7 | - | 1.0 | 1 | 0 | 0 | 1 |
| Apr 15 | vs COL | W 3-1 | S | 1.0 | 0 | 0 | 0 | 2 |
| Apr 14 | vs COL | W 7-6 | S | 0.1 | 0 | 0 | 0 | 1 |
| Apr 12 | @SEA | L 1-6 | - | 1.1 | 0 | 0 | 0 | 0 |
| Apr 10 | @SEA | L 6-9 | - | 1.0 | 1 | 0 | 0 | 1 |
| Apr 8 | @COL | L 1-9 | - | 2.0 | 2 | 1 | 1 | 2 |
| Apr 6 | @COL | L 7-9 | - | 1.0 | 1 | 0 | 0 | 0 |
| 2025 season | ||||||||
| Sep 27 | @LAA | W 6-1 | - | 1.0 | 0 | 0 | 0 | 2 |
| Sep 25 | @ATH | W 11-5 | - | 1.0 | 3 | 2 | 0 | 1 |
| Sep 23 | @ATH | L 1-5 | - | 1.0 | 1 | 1 | 1 | 1 |
| Sep 21 | vs SEA | L 3-7 | - | 1.2 | 0 | 0 | 1 | 1 |
| Sep 19 | vs SEA | L 0-4 | - | 1.0 | 2 | 1 | 0 | 0 |
| Sep 16 | vs TEX | W 6-5 | - | 0.2 | 3 | 4 | 1 | 0 |
| Sep 14 | @ATL | L 3-8 | - | 1.0 | 1 | 0 | 0 | 3 |
| Sep 13 | @ATL | W 6-2 | - | 1.0 | 2 | 0 | 0 | 2 |
| Sep 10 | @TOR | W 3-2 | W | 0.2 | 1 | 0 | 0 | 1 |
| Sep 9 | @TOR | L 3-4 | - | 0.1 | 2 | 1 | 0 | 0 |
| Sep 6 | @TEX | W 11-0 | - | 1.0 | 0 | 0 | 1 | 2 |
| Sep 4 | vs NYY | L 4-8 | - | 1.2 | 0 | 0 | 1 | 1 |
| Sep 2 | vs NYY | L 1-7 | - | 2.0 | 1 | 0 | 0 | 2 |
| Aug 30 | vs LAA | L 1-4 | - | 0.1 | 0 | 0 | 0 | 1 |
| Aug 29 | vs LAA | W 2-0 | W | 1.0 | 2 | 0 | 0 | 1 |
| Aug 28 | vs COL | W 4-3 | - | 0.1 | 0 | 0 | 0 | 0 |
| Aug 23 | @BAL | W 9-8 | - | 1.0 | 1 | 0 | 0 | 2 |
| Aug 22 | @BAL | W 10-7 | - | 1.0 | 1 | 1 | 1 | 2 |
| Aug 20 | @DET | L 2-7 | - | 1.0 | 0 | 0 | 0 | 1 |
| Aug 17 | vs BAL | L 0-12 | - | 0.2 | 1 | 0 | 0 | 0 |
| Aug 16 | vs BAL | W 5-4 | W | 2.0 | 0 | 0 | 0 | 1 |
| Aug 11 | vs BOS | W 7-6 | - | 1.0 | 1 | 0 | 0 | 0 |
| Jul 29 | @KC | L 6-9 | - | 1.2 | 4 | 3 | 1 | 0 |
| Jul 26 | @TEX | L 5-6 | L | 0.0 | 1 | 0 | 1 | 0 |
| Jul 25 | @TEX | L 3-8 | - | 1.0 | 0 | 0 | 1 | 1 |
| Jul 21 | vs SF | W 9-5 | - | 2.0 | 2 | 1 | 0 | 1 |
| Jul 19 | vs NYY | L 9-12 | - | 0.0 | 3 | 3 | 1 | 0 |
| Jul 11 | @STL | W 6-5 | W | 2.0 | 0 | 0 | 0 | 1 |
| Jul 8 | @ATH | L 1-10 | - | 1.2 | 0 | 0 | 0 | 1 |
| Jul 5 | vs BAL | L 6-9 | - | 0.2 | 0 | 0 | 1 | 1 |
| Jul 3 | vs LAA | L 1-5 | - | 1.0 | 1 | 1 | 1 | 1 |
| Jul 1 | vs LAA | L 0-4 | - | 0.2 | 2 | 0 | 1 | 0 |
| Jun 27 | vs PHI | L 0-13 | - | 1.1 | 2 | 0 | 0 | 1 |
| Jun 24 | @NYM | W 7-4 | - | 0.1 | 2 | 1 | 0 | 0 |
Latest news
The Astros placed De Los Santos on the 15-day injured list Saturday with right knee tendinitis, Matt Kawahara of the Houston Chronicle reports.
De Los Santos gave up two runs over two innings during his appearance Friday and now appears to have picked up an injury in the process. His trip to the injured list will rule him out for the rest of the regular season, so he'll finish the campaign with a 4.79 ERA and 1.25 WHIP through 71.1 innings. Logan VanWey was recalled from Triple-A in a corresponding move.
RotoWire via ESPN · Sep 19
De Los Santos secured the save Thursday against the Tigers, allowing one run on two hits and no walks in the ninth inning. He did not record a strikeout.
De Los Santos served up a solo home run to Dillon Dingler before letting the possible tying run get aboard, but Colt Keith grounded into a double play to end the game. Closer Josh Hader worked each of the past two days, so De Los Santos should revert back to a setup role going forward. The right-hander has a 4.79 ERA, 1.18 WHIP and 33:8 K:BB over 35.2 innings while converting five of his seven save chances.
RotoWire via ESPN · Jun 26
De Los Santos (0-2) took the loss Monday against the Blue Jays, allowing a run on two hits while striking out two over 1.1 innings.
De Los Santos looked good in the sixth inning, setting down the top of Toronto's lineup in order, but he'd give up a pair of hits after coming back out in the seventh and ultimately took the loss in a 4-2 defeat. It's been a tough stretch of late for De Los Santos of late -- he's given up seven runs on nine hits in his last 6.1 innings. Overall, the right-hander sports a 4.32 ERA with a 1.11 WHIP and 33:8 K:BB across 33.1 innings this year.
RotoWire via ESPN · Jun 23
De Los Santos struck out three over 1.2 perfect innings to earn the save in Wednesday's 4-3 win over the Rangers.
This was De Los Santos' first save in over a month. He got the nod in the eighth inning after Bryan King struggled mightily to open the frame. A rough patch in late April seemingly cost De Los Santos consistent high-leverage work, but he's gotten back in the mix by allowing just two runs (one earned) over 9.2 innings in his last nine appearances. He's at a 3.57 ERA, 1.01 WHIP and 21:4 K:BB with four saves and four holds over 22.2 innings this season. His time competing with King and Bryan Abreu for regular save chances is nearing an end, as Josh Hader (biceps) is expected back in the first week of June.
RotoWire via ESPN · May 28
De Los Santos gave up a hit and a walk over 1.1 scoreless innings Wednesday to record his third save of the season in a 2-0 win over the Guardians. He struck out one.
The journeyman righty wrapped up the combined shutout on 24 pitches (16 strikes), although De Los Santos did make things interesting by putting the tying runner on base in the ninth inning with two outs. He's converted three straight save chances since April 14, emerging as the preferred closing option for manager Joe Espada while the Astros continue to navigate the absence of Josh Hader (bicep), but De Los Santos' 3.86 ERA, 1.18 WHIP and 8:3 K:BB through 9.1 innings this season don't suggest he'll have a long-term spot in the team's high-leverage crew.
RotoWire via ESPN · Apr 22
De Los Santos (0-1) took the loss Tuesday against the Guardians, allowing three runs on two hits and a walk in one-third of an inning.
Tasked with protecting a two-run lead in the eighth inning, De Los Santos allowed three of the four batters he faced to reach safely, opening the door for Cleveland's six-run frame. Prior to Tuesday, De Los Santos had given up just one run across 7.2 innings in his first seven appearances this season while seeing closing opportunities in the absence of Josh Hader (biceps).
RotoWire via ESPN · Apr 22