NFL Week 10 Thursday Practice Report: Patrick Mahomes Is Full Again, Ladd McConkey Sits and Josh Jacobs and TreVeyon Henderson Are Out

Thursday's Week 10 practice reports sharpened the picture for Sunday's slate. Patrick Mahomes was a full participant for the second straight day and is on track to start at Atlanta. Ladd McConkey did not practice with a back issue ahead of the Chargers' Monday night trip to Baltimore. And a group of fantasy-relevant players has already been ruled out, led by Green Bay's Josh Jacobs, New England's TreVeyon Henderson and Seattle's Sam Darnold. Here is where every key status stands heading into Friday's final reports.

The headline statuses

The table below covers the fantasy-relevant names with confirmed practice participation or game status as of Thursday.

Quarterbacks

Patrick Mahomes (Chiefs at Falcons): The elbow scare from Week 9 has faded. Mahomes was hit on his throwing arm on a strip-sack in the win over the Jets, an MRI showed no significant damage, and head coach Andy Reid said early in the week that Mahomes was throwing the ball well. Back-to-back full practices make him a confident start. One report listed a knee alongside the elbow on Thursday's report, which other outlets did not mention, so watch the final listing on Friday, but nothing suggests he is at risk of missing the game.

Sam Darnold (Seahawks at Raiders): Ruled out with quad and rib injuries. Drew Lock makes his second straight start, and Seattle's Week 11 bye gives Darnold a path to return in Week 12.

Running backs

Josh Jacobs (Packers vs. Vikings): Out with a fractured ring finger that requires surgery. Reports indicate a return window of roughly two to three weeks. Green Bay's backfield work shifts to the depth chart behind him, and Jacobs managers need a replacement for at least this week and likely the next.

TreVeyon Henderson (Patriots vs. Lions in Munich): Out with an undisclosed medical issue. With Rhamondre Stevenson already sidelined for weeks, New England's backfield is in flux heading into Germany. Corey Kiner is the waiver-wire name who stands to take on the most work.

Travis Etienne Jr. (Saints vs. Panthers): Limited both days after the Saints opened his window to return from injured reserve. New Orleans must activate him by Saturday afternoon for him to play. Alvin Kamara was also listed on Thursday's report with rest and back.

Receivers

Ladd McConkey (Chargers at Ravens, Monday): McConkey did not practice Thursday with a back issue, the same problem that kept him from playing a snap in Week 9 after back spasms hit during pregame warmups. Head coach Jim Harbaugh has described him as day-to-day, and the Chargers have until Saturday to issue a final designation. He was one of nine Chargers who did not practice Thursday, a list that also included Khalil Mack (rest) and Daiyan Henley (personal). With a Monday game, the Chargers can wait longer than most teams, which makes McConkey a likely late decision.

Garrett Wilson (Jets vs. Bills): Limited again in the concussion protocol. Aaron Glenn has said he is very hopeful Wilson plays, but he has not been cleared.

Mike Evans (49ers at Cowboys) and Zachariah Branch (Falcons vs. Chiefs): Both remain sidelined. San Francisco's new addition Keenan Allen steps into a larger role, and Atlanta continues without Branch.

Defense and the big Sunday night game

Lions (vs. Patriots in Munich): Detroit ruled out three players before traveling to Germany, including safety Kerby Joseph, and cornerback D.J. Reed is also out with a hip injury. A secondary that thin is a boost for New England's passing game.

Bengals and Steelers (Sunday night): Cincinnati designated cornerback Jalen Davis, receiver Andrei Iosivas and guard Brian Parker II to return from injured reserve, and all three practiced fully on Thursday. Safety Kyle Dugger (quad) and defensive tackle Jonathan Allen (rest) did not practice. For Pittsburgh, Cameron Heyward had a rest day and T.J. Watt was limited for rest, both routine veteran maintenance. Defensive lineman Derrick Harmon returned to practice from injured reserve on a limited basis. Joe Burrow does not appear on the report.

Fantasy fallout

Start with confidence: Patrick Mahomes. Two full practices remove the doubt.

Have a backup plan: Ladd McConkey and Garrett Wilson. McConkey's Monday kickoff is a problem for managers who start him, because his status may not be resolved until after Sunday's games. Pivot to a Sunday receiver unless McConkey practices fully by Saturday.

Find replacements: Josh Jacobs and TreVeyon Henderson managers. Check the waiver wire for Green Bay and New England backups and for Corey Kiner in particular.

Upgrade: The Patriots passing game against Detroit's depleted secondary, and the Seahawks defense against a Raiders offense led by a rookie quarterback.

Betting angle

Most of these statuses were priced into the market early in the week. The ones that can still move numbers are McConkey's (the Chargers' passing game is thin without him) and Wilson's (the Jets' offense loses its only reliable target if he sits). Mahomes' full participation removes the biggest risk on the board.

For Verdexed's model view on each game, see the weekly NFL picks page and /nfl/predictions.

What's next

Friday brings final designations for every Sunday game. Saturday brings the Saints' Etienne activation deadline and the Chargers' final report for Monday night. Check back before lineups lock, especially for players listed as questionable.